<Grid >
<Grid.ColumnDefinitions>
<ColumnDefinition Width="2*" /><!--This will make any control in this column of grid take 2/5 of total width-->
<ColumnDefinition Width="3*" /><!--This will make any control in this column of grid take 3/5 of total width-->
</Grid.ColumnDefinitions>
<Grid.RowDefinitions>
<RowDefinition MinHeight="30" />
</Grid.RowDefinitions>
<TextBlock Grid.Column="0" Grid.Row="0">Your text block a:</TextBlock>
<TextBlock Grid.Column="1" Grid.Row="0">Your text block b:</TextBlock>
</Grid>