I know it's a bit crowded. I was using it with my program and felt the desire to share it with people. It can tell if any character in a string is not a letter or not. Use it if you want something easy to clarify and look back on.
I used this regex expression (".*[a-zA-Z]+.*"). With if not statement it will avoid all expressions that have a letter before, at the end or between any type of other character.
While there are many ways to skin this cat, I prefer to wrap such code into reusable extension methods that make it trivial to do going forward. When using extension methods, you can also avoid RegEx as it is slower than a direct character check. I like using the extensions in the Extensions.cs NuGet package. It makes this check as simple as:
"smith23".IsAlphabetic() will return False whereas "john smith".IsAlphabetic() will return True. By default the .IsAlphabetic() method ignores spaces, but it can also be overridden such that "john smith".IsAlphabetic(false) will return False since the space is not considered part of the alphabet.
Every other check in the rest of the code is simply MyString.IsAlphabetic().