Unless your compiler is different than the one supplied with the Mac XCode Dev tools, just follow the instructions in section 5.1 of Getting Started Guide for Unix Variants. The configuration and building of the latest source couldn't be easier, and it took all about about 1 minute to configure and 10 minutes to compile.
Just get the source, and compile Boost yourself; it has become very easy. Here is an example for the current version of Boost on the current macOS as of this writing:
One thing to note: in order for that to make a difference you need to have built python with +universal, if you haven't or you're not sure you can just rebuild python +universal. This applies to both brew as well as macports.
$ brew reinstall python
$ brew install boost
OR
$ sudo port -f uninstall python
$ sudo port install python +universal
$ sudo port install boost +universal